从再生大鼠肝脏分离的线粒体的呼吸控制指数
Respiratory control index of mitochondria isolated from regenerating rat liver.
作者信息
Svátková R, Cervinková Z, Kalous M, Rauchová H, Drahota Z
机构信息
Department of Physiology, Faculty of Medicine, Charles University, Hradec Králové, Czech Republic.
出版信息
Physiol Res. 1996;45(3):249-52.
Mitochondria were isolated from regenerating rat liver 12, 24 and 48 h after partial hepatectomy. The "State 3" and "State 4" respiration were measured in the presence of succinate. The P/O quotient and respiratory control index (RCI) were calculated. The experimental data showed that the partial uncoupling of oxidative phosphorylation in regenerating liver mitochondria occurring in the early period of regeneration is partly due to free fatty acids.
在部分肝切除术后12、24和48小时，从再生大鼠肝脏中分离出线粒体。在琥珀酸存在的情况下测量“状态3”和“状态4”呼吸。计算P/O商和呼吸控制指数（RCI）。实验数据表明，再生早期肝脏线粒体氧化磷酸化的部分解偶联部分归因于游离脂肪酸。
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