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Liquid chromatographic analysis of cocaine and benzoylecgonine in plasma of traditional coca chewers from Bolivia during exercise.

作者信息

Rerat C, Sauvain M, Rop P P, Ruiz E, Bresson M, Viala A

机构信息

Instituto Boliviano de Biología de Altura, Universidad Mayor de San Andres, La Paz, Bolivia.

出版信息

J Ethnopharmacol. 1997 May;56(3):173-8. doi: 10.1016/s0378-8741(97)00029-9.

DOI:10.1016/s0378-8741(97)00029-9
PMID:9201606
Abstract

The purpose of the present study was to determine the amount of cocaine and benzoylecgonine in the plasma of Aymara Indians from the Bolivian Andes after traditional chewing of coca leaves during exercise performance. The determination was carried out by high performance liquid chromatography after solid-liquid extraction. The results showed that such use of coca leaves is well correlated with pharmacologically active concentration of cocaine in plasma.

摘要

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