Washio M, Okuda S, Mizoue T, Kiyama S, Ando T, Sanai T, Hirakata H, Nanishi F, Kiyohara C, Ogimoto I, Yoshimura T, Fujishima M
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Clin Nephrol. 1997 Jun;47(6):362-6.
Left ventricular hypertrophy is reported to be common in chronic hemodialysis patients, and also to increase the risk for mortality in chronic hemodialysis patients. An echocardiographical and clinical study was carried out to investigate the risk factors for left ventricular hypertrophy in 151 non-diabetic chronic hemodialysis patients without valvular diseases or myocardial infarction in two hemodialysis units in Fukuoka, Japan. The left ventricular mass index (LVMI) correlated positively to age, systolic blood pressure and interdialysis weight gain while it correlated negatively to the duration of hemodialysis therapy and hematocrit. Resorting to a multivariate analysis, the LVMI was found to positively correlate to age and the systolic blood pressure while it correlated negatively with the duration of hemodialysis therapy and the hematocrit level. These findings suggest that hypertension and anemia may thus be independent risk factors for left ventricular hypertrophy.
据报道，左心室肥厚在慢性血液透析患者中很常见，并且还会增加慢性血液透析患者的死亡风险。在日本福冈的两个血液透析单位，对151名无瓣膜疾病或心肌梗死的非糖尿病慢性血液透析患者进行了一项超声心动图和临床研究，以调查左心室肥厚的危险因素。左心室质量指数（LVMI）与年龄、收缩压和透析间期体重增加呈正相关，而与血液透析治疗时间和血细胞比容呈负相关。通过多变量分析发现，LVMI与年龄和收缩压呈正相关，而与血液透析治疗时间和血细胞比容水平呈负相关。这些发现表明，高血压和贫血可能是左心室肥厚的独立危险因素。
