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联络临床药师对住院姑息治疗病房的贡献。

Contribution of a liaison clinical pharmacist to an inpatient palliative care unit.

作者信息

Lucas C, Glare P A, Sykes J V

机构信息

HIV/AIDS Unit, Royal Prince Alfred Hospital, Sydney, Australia.

出版信息

Palliat Med. 1997 May;11(3):209-16. doi: 10.1177/026921639701100305.

Abstract

The impact on patient care of interventions made by a liaison clinical pharmacist visiting a busy inpatient palliative care unit were evaluated using a validated six-point scoring system. Interventions made in 13% of patients could improve patient care, save money or both, but rarely involved the drugs that are commonly used for symptom control in patients with terminal cancer. Advice to rationalize inappropriate drug regimens (53%) was the commonest intervention, followed by warnings about drug interactions (24%) and advice about therapeutic drug monitoring (8%). The interventions were evaluated by the pharmacist, a palliative medicine registrar and two independent doctors, confirming that the pharmacist was valid and accurate in assessing her own work. Although more than 60% of interventions could significantly improve patient care, compliance by medical and nursing staff with advice was only 55%, reflecting possible tensions between palliative and general hospital medicine. This survey emphasizes the role of liaison clinical pharmacists in palliative care, the need for much more critical appraisal of prescribing practices and the utility of ranking pharmacist interventions as a quality assurance and educational tool. In particular, providing palliative care for patients with advanced acquired immunodeficiency syndrome (AIDS) is enhanced when a pharmacist with a specialist knowledge of AIDS therapeutics is available.

摘要

采用经过验证的六点评分系统,评估了联络临床药师走访繁忙的住院姑息治疗病房所进行的干预措施对患者护理的影响。在13%的患者中实施的干预措施可改善患者护理、节省费用或两者兼得,但很少涉及晚期癌症患者常用的症状控制药物。使不适当的药物治疗方案合理化的建议(53%)是最常见的干预措施,其次是关于药物相互作用的警告(24%)和关于治疗药物监测的建议(8%)。这些干预措施由药师、姑息医学住院医师和两名独立医生进行评估,证实药师在评估自己的工作时是有效且准确的。尽管超过60%的干预措施可显著改善患者护理,但医护人员对建议的依从性仅为55%,这反映出姑息治疗与综合医院医学之间可能存在的矛盾。这项调查强调了联络临床药师在姑息治疗中的作用、对处方实践进行更严格评估的必要性,以及将药师干预措施进行排名作为质量保证和教育工具的实用性。特别是,当有具备艾滋病治疗专业知识的药师时,为晚期获得性免疫缺陷综合征(AIDS)患者提供的姑息治疗会得到加强。

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