Wang X F, Shi D Z, Tu X H
Xiyuan Hospital, China, Academy of TCM, Beijing.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1996 Apr;16(4):201-3.
One hundred twenty-two patients with spontaneous angina pectoris (SAP) were randomly divided into treated group (82 cases) and control group (40 cases), and treated with Wenxin decoction and isosorbide dinitrate respectively. Results showed that in treated group the total effective rate of SAP was 95.12% and that of electrocardiographic findings were 74.39%. These results were all superior to those of control group (P < 0.01). Moreover, results of extracorporeal thrombosis test showed after Wenxin decoction treatment, the length of thrombus decreased from 23.56 +/- 5.47 mm to 20.04 +/- 5.17 mm, the wet weight of it decreased from 92.65 +/- 18.45 mg to 76.94 +/- 15.08 mg and the dry weight from 21.76 +/- 7.30 mg to 16.90 +/- 5.35 mg. The submaximal exercise test revealed an increase of exercise time from 474.66 +/- 96.33 seconds to 548.83 +/- 99.93 seconds, increase of acting quantity from 104.16 +/- 19.65 W to 123.61 +/- 24.96 W and a decrease of ST segment depression from 0.183 +/- 0.041 mV to 0.139 +/- 0.038 mV. These results suggested that Wenxin decoction is valuable in treating SAP.
122例自发性心绞痛（SAP）患者随机分为治疗组（82例）和对照组（40例），分别给予温心汤和硝酸异山梨酯治疗。结果显示，治疗组SAP总有效率为95.12%，心电图疗效为74.39%。这些结果均优于对照组（P<0.01）。此外，体外血栓形成试验结果显示，温心汤治疗后，血栓长度从23.56±5.47mm降至20.04±5.17mm，湿重从92.65±18.45mg降至76.94±15.08mg，干重从21.76±7.30mg降至16.90±5.35mg。次极量运动试验显示运动时间从474.66±96.33秒增加至548.83±99.93秒，做功量从104.16±19.65W增加至123.61±24.96W，ST段压低从0.183±0.041mV降至0.139±0.038mV。这些结果提示温心汤治疗SAP有一定价值。
