Di Vita G, Frazzetta M, Matranga S, Migliore G, Bellisi M, Cortese E
Dipartimento di Discipline Chirurgiche ed Anatomiche, Università degli Studi di Palermo.
G Chir. 1997 Jan-Feb;18(1-2):19-22.
The aim of this study is to evaluate, after laparoscopic (CL) or open (CO) cholecystectomy, the incidence of pulmonary atelectasis and hypoxaemia which are strictly related to the onset of pulmonary complications. Two groups of 20 consecutive patients affected by symptomatic and not complicated gallstone disease were cholecystectomized either using CO or CL. Hypoxaemia was assessed preoperatively and after operation. Postoperative determination was performed at the 4th, 8th, 12th and 24th hour and then every 12 hours until discharge from hospital. A not informed radiologist evaluated atelectasis through two X-rays, preoperatively and postoperatively at the 3rd day. Atelectasis cases were divided in micro, focal, segmental, lobar and of the entire lung. Statistic analysis was performed using the "t" Student test. No mortality or intraoperative complications occurred. The two groups were similar for age, sex, smoker percentage, obesity, preexisting pulmonary dysfunctions and anaesthesiological risk (ASA). Operative time resulted in longer in CL compared to CO patients although in an insignificant way. PO2 value resulted significatively reduced (P < 0.05) at 4th, 8th, 12th and 24th postoperative hour after CO, while subsequent measurements did not show significant differences. There was no evidence of PO2 significative reduction after CL. After operation atelectasis was found in 11 patients (55%) of CL group (P < 0.05) and in 17 patients (85%) of CO group (P < 0.001). Atelectasis observed in the group of 11 CL patients was represented by 7 micro and 4 focal types, while in the CO group 7 micro, 8 focal and 2 segmental types were found. This study suggests that CL alters the pulmonary function less than CO.
本研究的目的是评估腹腔镜(CL)或开腹(CO)胆囊切除术后与肺部并发症发生密切相关的肺不张和低氧血症的发生率。两组各20例连续的有症状且无并发症的胆结石病患者,分别接受CO或CL胆囊切除术。术前及术后评估低氧血症情况。术后测定在第4、8、12和24小时进行,然后每12小时测定一次,直至出院。一名不知情的放射科医生通过术前和术后第3天的两张X光片评估肺不张情况。肺不张病例分为微小、局灶、节段、叶和全肺型。采用学生“t”检验进行统计学分析。未发生死亡或术中并发症。两组在年龄、性别、吸烟率、肥胖、既往肺部功能障碍和麻醉风险(ASA)方面相似。CL组的手术时间虽比CO组患者长,但差异不显著。CO组术后第4、8、12和24小时的PO2值显著降低(P < 0.05),而后续测量未显示显著差异。CL术后未发现PO2有显著降低。术后,CL组11例患者(55%)出现肺不张(P < 0.05),CO组17例患者(85%)出现肺不张(P < 0.001)。CL组11例患者中观察到的肺不张表现为7例微小和4例局灶型,而CO组发现7例微小、8例局灶和2例节段型。本研究表明,CL对肺功能的影响小于CO。