Misra S, Tyagi K, Chatterjee R K
Division of Parasitology, Central Drug Research Institute, Lucknow, India.
Exp Parasitol. 1997 Jun;86(2):155-7. doi: 10.1006/expr.1997.4169.
Successful experimental transmission of the human lymphatic dwelling nocturnal periodic strain of Wuchereria bancrofti has been achieved from man to Indian leaf monkey (Presbytis entellus) through a susceptible strain of Aedes aegypti. The prepatent period varied between 195 and 240 days. Microfilaria (mf) levels were in general low and the peak count was attained at 1800 hr. Of the adult worms 5-12.5% were recovered from male langur while females revealed poor (2.54%) recovery. This host--parasite model thus makes available the target parasite material in substantial quantity to work on chemotherapeutic and immunological investigations.
通过易感的埃及伊蚊品系，已成功将班氏吴策线虫的人体淋巴宿主体夜周期型从人传播至印度叶猴（食蟹猴）。潜伏期在195至240天之间。微丝蚴水平总体较低，高峰计数出现在18:00。在成年虫中，从雄性叶猴体内回收的占5%-12.5%，而从雌性叶猴体内回收的比例较低（2.54%）。因此，这种宿主-寄生虫模型可提供大量目标寄生虫材料，用于化疗和免疫学研究。
