Gnanadurai T V, Branthwaite M A, Colbeck J F, Welman E
Anaesthesia. 1977 Sep;32(8):743-8. doi: 10.1111/j.1365-2044.1977.tb10074.x.
Lysosomal enzyme release occurs during cardiopulmonary bypass in man but the tissues from which these enzymes originate have not been identified. The activity of N-acetyl beta-glucosaminidase in plasma increases to a degree which is proportional to the duration of bypass and this enzyme may therefore be a better marker than beta-glucuronidase of tissue damage caused by cardiopulmonary bypass, as distinct from tissue damage solely to the operative procedure.
溶酶体酶的释放发生在人体体外循环期间，但这些酶的来源组织尚未明确。血浆中N - 乙酰 -β-氨基葡萄糖苷酶的活性增加到一定程度，且与体外循环的持续时间成正比，因此与仅由手术操作导致的组织损伤不同，这种酶可能是比β-葡萄糖醛酸酶更好的体外循环所致组织损伤的标志物。
