Sayegh F S, Abousy A
Anat Rec. 1977 Nov;189(3):451-65. doi: 10.1002/ar.1091890306.
Incisor and molar tooth germs of albino rats sacrificed at the eighteenth and twentieth days in utero and one to seven days after birth were studied with light and electron microscopy. Observations of the various stages of tooth development in molars established that intramitochondrial granules in odontoblasts were comparable to the intramitochondrial granules of other hard tissue cells. These electron-dense deposits appeared in mitochondria in an appreciable number only when odontoblasts become engaged in dentin mineralization. When dentin mineralization was advanced the odontoblast mitochondria appeared devoid of these deposits. Mesenchymal cells and preodontoblasts of the pulp were not involved in this activity.
对在子宫内第18天和第20天以及出生后1至7天处死的白化大鼠的切牙和磨牙牙胚进行了光镜和电镜研究。对磨牙牙齿发育各个阶段的观察表明，成牙本质细胞中的线粒体内颗粒与其他硬组织细胞中的线粒体内颗粒相当。这些电子致密沉积物仅在成牙本质细胞参与牙本质矿化时才大量出现在线粒体中。当牙本质矿化进展时，成牙本质细胞线粒体似乎没有这些沉积物。牙髓的间充质细胞和前成牙本质细胞不参与此活动。
