Sinforiani E, Livieri C, Mauri M, Bisio P, Sibilla L, Chiesa L, Martelli A
Neuropsychology Unit, IRCCS C. Mondino, Italy.
Psychoneuroendocrinology. 1994;19(1):55-64. doi: 10.1016/0306-4530(94)90059-0.
Nineteen patients with congenital adrenal hyperplasia (CAH) aged over 16 years were given a neuropsychological evaluation; no significant differences with individually matched normal controls were detected. CAH subjects, however, revealed slightly higher IQs with respect to the expected distribution. No significant learning disabilities could be detected. Fifteen patients underwent nuclear magnetic resonance (NMR); 4 subjects showed small areas of increased signal intensity in the white matter, without prevalence of side; this finding did not correlate with clinical and cognitive characteristics. The results are discussed in the light of possible hormonal influences.
对19名年龄超过16岁的先天性肾上腺增生症（CAH）患者进行了神经心理学评估；未发现与个体匹配的正常对照组有显著差异。然而，CAH受试者的智商相对于预期分布略高。未检测到明显的学习障碍。15名患者接受了核磁共振（NMR）检查；4名受试者白质出现小面积信号强度增加，无侧别优势；这一发现与临床和认知特征无关。根据可能的激素影响对结果进行了讨论。
