Frazier J A, Field C M
Department of Biochemistry and Biophysics, UCSF Medical Center, San Francisco, California 94143-0448, USA.
Curr Biol. 1997 Jul 1;7(7):R414-7. doi: 10.1016/s0960-9822(06)00205-3.
The FH proteins, defined by the presence of 'formin homology' regions, are important for a number of actin-dependent processes, including polarized cell growth and cytokinesis. They are large, probably multi-domain, proteins and their function may be in part mediated by an interaction with profilin.
FH蛋白由“formin同源”区域的存在所定义,对许多肌动蛋白依赖性过程很重要,包括极化细胞生长和胞质分裂。它们是大型的、可能具有多个结构域的蛋白质,其功能可能部分由与profilin的相互作用介导。