粘褶菌代谢产物卵孢醇及一些合成类似物对靶细胞中蛋白质和RNA合成的影响。
Influence of the Gloeophyllum metabolite oosponol and some synthetic analogues on protein and RNA synthesis in target cells.
作者信息
Sonnenbichler J, Kovács T
机构信息
Max-Planck-Institut für Biochemie, Martinsried, Germany.
出版信息
Eur J Biochem. 1997 May 15;246(1):45-9. doi: 10.1111/j.1432-1033.1997.t01-2-00045.x.
Abstract
Oosponol [4-(hydroxyacetyl)-8-hydroxy-1H-2-benzopyran-1-one], a toxic metabolite of the basidiomycete Gloeophyllum abietinum, and some synthetic analogues were studied to clarify the molecular basis of their fungicidal, bactericidal, and phytotoxic effects. The antibiotic activity was due to a strong inhibition of RNA and protein synthesis in target cells.
摘要
奥索波诺醇[4-(羟基乙酰基)-8-羟基-1H-2-苯并吡喃-1-酮]，一种担子菌针叶口蘑的有毒代谢产物，以及一些合成类似物，为阐明它们的杀真菌、杀菌和植物毒性作用的分子基础而进行了研究。抗生素活性归因于对靶细胞中RNA和蛋白质合成的强烈抑制。
Zotero 插件