Metzler H, List W F
Wien Med Wochenschr. 1979 Sep 15;129(15):432-6.
30 patients with cardiac tachyarrhythmias were treated intra- and postoperatively with the new calciumantagonist Ro 11-1781. Atrial fibrillation, paroxysmal supraventricular tachycardia, supraventricular and ventricular extrasystoles and atrial tachycardia were the main indications. A good antiarrhythmic effect was noticed, provided that a dose of not less than 1 mg/kg was given. The mean fall of blood pressure was 4%, the maximal fall 15%.
30例心脏快速性心律失常患者在手术期间及术后使用新型钙拮抗剂Ro 11 - 1781进行治疗。主要适应证包括心房颤动、阵发性室上性心动过速、室上性及室性期前收缩和房性心动过速。若给予的剂量不少于1mg/kg,则可观察到良好的抗心律失常效果。平均血压下降4%,最大下降15%。