Nakano K, Eishi K, Kobayashi J, Sasako Y, Isobe F, Kosakai Y
National Cardiovascular Center, Osaka.
J Cardiol. 1997;29 Suppl 2:73-8.
The Toronto stentless porcine valve (TSPV) is a stentless porcine aortic valve, preserved with glutaraldehyde solution, which has been designed to maintain natural laminar blood flow and improve hemodynamic performance and enhance durability. Aortic valve replacement with TSPV was performed in seven patients. The reason for this indication was advanced age (65 years or more) in six patients and connective tissue disease in another patient. One patient required reoperation because of prosthetic valve endocarditis 4 months after implantation. There were no other valve-related complications. Echocardiographic examination of prosthetic valve function one month after surgery showed no aortic regurgitation in any patient. Transprosthetic gradient was 15.1 +/- 5.0 mmHg. Technical know-how is required for the implantation. The hemodynamic characteristics of the TSPV were excellent. Further follow-up is required to determine durability, but further extensive indication of this valve is expected as a bioprosthesis.
多伦多无支架猪瓣膜（TSPV）是一种经戊二醛溶液保存的无支架猪主动脉瓣膜，其设计目的是维持自然层流血液流动、改善血流动力学性能并提高耐用性。7例患者接受了TSPV主动脉瓣置换术。6例患者的手术指征为高龄（65岁及以上），另1例患者的指征为结缔组织病。1例患者在植入后4个月因人工瓣膜心内膜炎需要再次手术。未出现其他与瓣膜相关的并发症。术后1个月对人工瓣膜功能进行的超声心动图检查显示，所有患者均无主动脉瓣反流。跨人工瓣膜压差为15.1±5.0 mmHg。植入需要技术诀窍。TSPV的血流动力学特性极佳。需要进一步随访以确定其耐用性，但预计该瓣膜作为生物假体的适应证会进一步扩大。
