Recent structural solutions for antibody neutralization of viruses.
作者信息
Stewart P L, Nemerow G R
机构信息
Dept of Molecular and Medical Pharmacology, UCLA School of Medicine 90095-1770, USA.
出版信息
Trends Microbiol. 1997 Jun;5(6):229-33. doi: 10.1016/S0966-842X(97)01049-4.
PMID:9211643
Abstract
Structural studies of virus-antibody interactions can offer insights into mechanisms of virus neutralization and immune escape. Crystallography and cryoelectron microscopy can reveal the structural relationship between receptor-binding sites and neutralization epitopes, as well as whether molecular rearrangements occur upon antibody binding.
摘要
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