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[从副百日咳博德特氏菌提取物中分离组分及其在制备红细胞诊断制剂中的应用]

[Isolation of fractions from Bordetella parapertussis extracts and their use for preparing an erythrocyte diagnostic preparation].

作者信息

Samsonova V S, Kholchev N V, Mamaeva E A, Bakulina N A, Sulimov E N

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1979 Oct(10):76-80.

PMID:92121
Abstract

Soluble parapertusis antigen, serologically active, having hemosensitive properties and containing only 2 antigenic components was obtained by the method of ethanol fractionation of microbial extracts. This method is simple and convenient for production purposes. The antigen thus obtained was used for the production of a highly specific erythrocytic diagnostic preparation (formalinized, liquid). When tested in reaction with animal and human sera, the new diagnostic preparation proved to be sufficiently active and species specific.

摘要

通过微生物提取物乙醇分级分离法获得了具有血清学活性、具有血敏特性且仅含2种抗原成分的可溶性百日咳副菌抗原。该方法用于生产目的简单且方便。如此获得的抗原用于制备一种高度特异性的红细胞诊断制剂(福尔马林固定液状)。在与动物和人血清的反应测试中,这种新的诊断制剂被证明具有足够的活性且具有种属特异性。

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