Toyoshima H, Hayashi S, Tanabe N, Miyanishi K, Satoh T, Aizawa Y, Izumi T
Department of Public Health, Nagoya University School of Medicine, Japan.
Nagoya J Med Sci. 1996 Dec;59(3-4):81-95.
Epidemiological features, risk factors and preventive methods of sudden death (SD) derived from studies the authors have performed since 1987 together with colleagues in Niigata University School of Medicine were reviewed. When SD was defined as death occurring within 24 hours of the onset of symptoms, the annual incidence was 145/100,000 for people aged 15 years and older in Niigata Prefecture. The incidence increased sharply along with the advance of age, while the proportion of SD to natural death due to circulatory diseases was higher in younger people. Though diseases of the circulatory system made up approximately 90 percent of all causes of death, SD due to ischemic heart disease was less frequent in Japan than in western countries. SD showed various patterns in seasonal and "within-a-day" occurrences according to sex, age and cause of death. The months of the highest SD occurrence differed by occupation and matched the busiest work periods. A decrease in sleeping hours and mental stress experienced during the preceding week were related to the occurrence of both sudden death and non-fatal acute myocardial infarction. People having structural circulatory diseases were shown to be predisposed to SD when stress occurred, because fatal arrhythmia is easily induced by the above factors in such people. Health examinations were shown to have preventive effects, though limited, against SD. Differences in the resuscitated rates in cases where a witness was present and where one was not indicates that educating people about correct resuscitation methods is important to minimizing SD.
回顾了作者自1987年以来与新潟大学医学院的同事共同开展的研究中关于猝死(SD)的流行病学特征、危险因素和预防方法。当将猝死定义为症状发作后24小时内发生的死亡时,新潟县15岁及以上人群的年发病率为145/10万。发病率随年龄增长而急剧上升,而年轻人中猝死占循环系统疾病所致自然死亡的比例更高。尽管循环系统疾病约占所有死亡原因的90%,但在日本,缺血性心脏病导致的猝死比西方国家少见。根据性别、年龄和死因,猝死在季节和“一天内”的发生呈现出不同模式。猝死发生率最高的月份因职业而异,且与最繁忙的工作时期相符。睡眠时间减少和前一周经历的精神压力与猝死和非致命性急性心肌梗死的发生均有关。患有结构性循环系统疾病的人在压力出现时易发生猝死,因为上述因素在此类人群中容易诱发致命性心律失常。健康检查虽对猝死有预防作用,但效果有限。有目击者和没有目击者的情况下复苏率的差异表明,对人们进行正确复苏方法的教育对于将猝死降至最低很重要。