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[脑膜炎奈瑟菌引起的支气管肺炎——可能由一名去过香港的家庭成员传播]

[Bronchopneumonia caused by Neisseria meningitidis--probable transmission by a family member who had been in Hong Kong].

作者信息

Ohtaki M, Tabeta H, Suzuki Y

机构信息

Division of Internal Medicine, Funabashi Municipal Medical Center, Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1997 Apr;35(4):461-5.

PMID:9212675
Abstract

A 22-year-old man came to our hospital complaining of bloody sputum. No abnormalities were seen on a chest X-ray film, but computed tomography of the chest showed infiltrates in the middle and lower lung fields. Neisseria meningitidis was isolated from cultured samples of naso pharyngeal secretions, from sputum, and from a sample obtained during bronchoscopy; bacterial bronchopneumonia was diagnosed. Family members were studied for meningococcal infection, and the bacterium was cultured from a nasopharyngeal smear from the patient's mother. The mother was asymptomatic. Both bacteria belonged to Group B serum group and their drug sensitivities were equal. The patient's family had been in Hong Kong, where this bacterium is endemic, for two years. They then returned to Japan and started to live together with the patient nine months before the onset of symptoms. The mother may have become infected in Hong Kong and may have passed the bacterium to her son after her return. Oral ampicillin was effective in both mother and son. Investigation of the patient's family was necessary to establish the probable route of infection and to decide on the treatment.

摘要

一名22岁男性因咯血痰前来我院就诊。胸部X光片未见异常,但胸部计算机断层扫描显示中下肺野有浸润影。从鼻咽分泌物培养样本、痰液以及支气管镜检查获取的样本中分离出脑膜炎奈瑟菌;诊断为细菌性支气管肺炎。对患者家属进行了脑膜炎球菌感染研究,从患者母亲的鼻咽涂片培养出了该细菌。母亲没有症状。两种细菌均属于B血清群,且药敏性相同。患者一家在这种细菌流行的香港待了两年。之后他们返回日本,在症状出现前九个月开始与患者一起生活。母亲可能在香港感染了该细菌,并在返回后将其传染给了儿子。口服氨苄西林对母亲和儿子均有效。对患者家属进行调查对于确定可能的感染途径以及决定治疗方案很有必要。

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