Barson A J, Symonds J
Arch Dis Child. 1977 Aug;52(8):642-5. doi: 10.1136/adc.52.8.642.
Anterior pituitary glands from 200 fetuses and infants ranging in age from 22 weeks' gestation to one year of life were examined histologically for the presence of concretions. Characteristically these are round, lamellated bodies, often strongly basophilic, containing phosphates and measuring between 10 micrometer and 70 micrometer in diameter. They decreased in incidence postnatally and were rarely seen 6 months after birth. It is suggested that these concretions are a degenerative change in cells subject to the vigorous secretory activity that is part of the normal physiology of the anterior lobe of the pituitary from mid-gestation.
对200例年龄从妊娠22周直至1岁的胎儿及婴儿的垂体前叶进行了组织学检查，以确定是否存在结石。这些结石的特征是圆形、分层状的物体，通常具有很强的嗜碱性，含有磷酸盐，直径在10微米至70微米之间。它们在出生后的发生率降低，出生6个月后很少见到。有人认为，这些结石是细胞的一种退行性变化，这种变化发生在经历强烈分泌活动的细胞中，而强烈分泌活动是妊娠中期后垂体前叶正常生理的一部分。
