囊性纤维化患者病毒性下呼吸道疾病期间的血清补体降低
Serum complement depression during viral lower respiratory tract illness in cystic fibrosis.
作者信息
Strunk R C, Sieber O F, Taussig L M, Gall E P
出版信息
Arch Dis Child. 1977 Sep;52(9):687-90. doi: 10.1136/adc.52.9.687.
Abstract
Cystic fibrosis (CF) patients with viral lower respiratory tract illnesses (LRI) had depressed levels of the third and fourth components of complement, which returned to normal after recovery. There was no clinical evidence of immune complex disease. CF patients with LRI and no virus isolates, CF patients in stable status, and non-CF patients with LRI did not have complement depression. It is postulated that antigen-antibody complex activation of complement may occur in CF patients with viral LRI.
摘要
患有病毒性下呼吸道疾病（LRI）的囊性纤维化（CF）患者，其补体第三和第四成分水平降低，恢复后恢复正常。没有免疫复合物疾病的临床证据。患有LRI但未分离出病毒的CF患者、病情稳定的CF患者以及患有LRI的非CF患者没有补体降低的情况。据推测，补体的抗原-抗体复合物激活可能发生在患有病毒性LRI的CF患者中。
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