Sturge R A, Scott J T, Kennedy A C, Hart D P, Buchanan W W
Ann Rheum Dis. 1977 Oct;36(5):420-7. doi: 10.1136/ard.36.5.420.
Serum uric acid (SUA) was measured in 512 men and 254 women from two English regions and in 337 men from one Scottish region. Mean SUA levels were the same in the men (5-5 mg/100 ml) and similar in the women (3-9 and 4-1 mg/100 ml). The apparent rarity of gout in Scotsmen cannot be explained by regional differences in SUA levels or in the prevalence of hyperuricaemia (defined as SUA of 7-0 mg/100 ml or over) which was present in 6-6% of the English men and 8% of the Scots. SUA was positively correlated with weight and serum urea, and with age in women, but no variation was found with social class. Body weight was the most important predictor of SUA in both men and women and superior to measurements involving correction for height, such as ponderal index and calculated lean body mass.
在来自英格兰两个地区的512名男性和254名女性以及来自苏格兰一个地区的337名男性中测量了血清尿酸（SUA）。男性的平均SUA水平相同（5.5mg/100ml），女性的平均SUA水平相似（3.9和4.1mg/100ml）。苏格兰男性痛风明显罕见，这不能用SUA水平或高尿酸血症患病率（定义为SUA为7.0mg/100ml及以上）的地区差异来解释，高尿酸血症在6.6%的英格兰男性和8%的苏格兰男性中存在。SUA与体重、血清尿素呈正相关，在女性中与年龄也呈正相关，但未发现与社会阶层有关的差异。体重是男性和女性SUA的最重要预测因素，优于涉及身高校正的测量指标，如体质指数和计算的瘦体重。
