Haas E J, Madhavan T, Quinn E L, Cox F, Fisher E, Burch K
Arch Intern Med. 1977 Nov;137(11):1518-21.
We analyzed the clinical and laboratory findings of 19 patients with tuberculous meningitis seen between 1966 and 1974 at the Henry Ford Hospital. Eighteen patients were adults at the time of diagnosis. In eight patients, the history suggested that the infection with the tubercle bacillus had occurred in the remote past. Cerebrospinal fluid analysis was often typical for tuberculous meningitis; stains for Mycobacterium tuberculosis were usually negative. Of 16 patients who were treated, five died and five suffered permanent neurological sequelae. The addition to rifampin to isoniazid therapy did not improve either survival or permanent sequelae. We were not able to analyze the effect of steroids on the disease.
我们分析了1966年至1974年间在亨利·福特医院就诊的19例结核性脑膜炎患者的临床和实验室检查结果。18例患者在诊断时为成年人。8例患者的病史提示结核杆菌感染发生在遥远的过去。脑脊液分析通常符合结核性脑膜炎的特征；结核分枝杆菌染色通常为阴性。16例接受治疗的患者中，5例死亡，5例有永久性神经后遗症。在异烟肼治疗中加用利福平对生存率或永久性后遗症均无改善。我们无法分析类固醇对该疾病的影响。
