Wang G, Vannier M W, Skinner M W, Kalender W A, Polacin A, Ketten D R
Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110 USA.
IEEE Trans Biomed Eng. 1996 Sep;43(9):891-900. doi: 10.1109/10.532123.
Multielectrode, intracochlear implants were designed for individuals with profound sensorineural hearing loss who derive little or no benefit form acoustic hearing aids. Determination of each electrode's position in a patient's inner ear may improve speech processor programming to maximize speech recognition. In this paper, an approach is described to use as input a volumetric spiral computed tomography (CT) image of the Nucleus electrode array (Cochlear Pty. Ltd, Lane Cove, NSW, Australia) to unwrap it, and to measure its implanted length given starting and end points. Representative curvilinear structures were digitally synthesized in image volumes of isotropic 0.1-mm voxels. The electrode array was spirally CT-scanned in vitro and in vivo, and reconstructed on an isotropic grid in 0.1-mm steps. Two algorithms were constructed to track and measure these curvilinear structures. The first algorithm is Karhunen-Loeve (K-L)-transform based, in which the K-L transform is locally applied at a current main axis position to determine the eigenvectors of the main axis voxels, the next main axis position is estimated from the current position along the principal eigendirection, adjusted to the mass center of the orthogonal cross section passing through the estimated position, and then scaled to have a prespecified step. The second algorithm is similar to the first one but avoids use of the K-L transform. In the second algorithm, the next position is directly estimated along the local direction and then processed with the same correction and scaling operations. With user-specified starting and end points as well as a local direction at the starting point, a curvilinear structure can be automatically tracked using either of the algorithms. The first algorithm is more robust, while the second one is more efficient. In the numerical and in vitro studies, the lengths of the curvilinear structures were accurately measured. Given local directions determined in the tracking process, an electrode array image can be unwrapped into a linear array with the central electrode axis as the abscissa. The unwrapping approach allows longitudinally and cross-sectionally accurate measurement and better visualization of cochlear implant images. With preimplantation knowledge of length, width, and center electrode distance, the position of individual electrodes can be estimated after unwrapping.
多电极人工耳蜗植入装置是为那些患有严重感音神经性听力损失、使用声学助听器几乎没有或根本没有获益的个体设计的。确定每个电极在患者内耳中的位置,可能会改善言语处理器的编程,以最大限度地提高言语识别能力。在本文中,描述了一种方法,即将澳大利亚新南威尔士州莱恩科夫市科利耳有限公司的Nucleus电极阵列的容积螺旋计算机断层扫描(CT)图像作为输入,展开该图像,并在给定起点和终点的情况下测量其植入长度。在各向同性体素为0.1毫米的图像容积中,以数字方式合成了代表性的曲线结构。电极阵列在体外和体内进行了螺旋CT扫描,并以0.1毫米的步长在各向同性网格上重建。构建了两种算法来跟踪和测量这些曲线结构。第一种算法基于卡尔胡宁-洛伊夫(K-L)变换,其中K-L变换在当前主轴位置局部应用,以确定主轴体素的特征向量,下一个主轴位置从当前位置沿主特征方向估计,调整到通过估计位置的正交横截面的质心,然后按比例缩放以具有预定步长。第二种算法与第一种算法类似,但避免使用K-L变换。在第二种算法中,下一个位置直接沿局部方向估计,然后进行相同的校正和缩放操作。有了用户指定的起点和终点以及起点处的局部方向,使用这两种算法中的任何一种都可以自动跟踪曲线结构。第一种算法更稳健,而第二种算法更高效。在数值研究和体外研究中,准确测量了曲线结构的长度。根据跟踪过程中确定的局部方向,可以将电极阵列图像展开为以中心电极轴为横坐标的线性阵列。这种展开方法允许对人工耳蜗图像进行纵向和横向的精确测量以及更好的可视化。有了植入前关于长度、宽度和中心电极距离的知识,展开后可以估计各个电极的位置。