Arnold W
Arch Geschwulstforsch. 1977;47(4):335-45.
The present paper describes experiments on artificial hematogenous metastasation of chemically induced tumours in mice and rats. Total-body irradiation prior to tumour cell application greatly increased metastatic dissemination. The metastasation is significantly inhibited by pretreatment of the animals with a carcinogenic agent. Similarly, a significant inhibition of metastatic growth was observed in primary tumour animals after surgery.
本文描述了在小鼠和大鼠中对化学诱导肿瘤进行人工血行转移的实验。在接种肿瘤细胞之前进行全身照射可大大增加转移扩散。用致癌剂对动物进行预处理可显著抑制转移。同样，在原发性肿瘤动物手术后观察到转移生长受到显著抑制。
