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[进行性肌营养不良患者肌肉中琥珀酸脱氢酶和乳酸脱氢酶活性的变化]

[Changes in the activity of succinate dehydrogenase and lactate dehydrogenase in the muscles of patients with progressive muscular dystrophy].

作者信息

Semenova-Tian-Shanskaia V V, Saikova L A

出版信息

Arkh Patol. 1977;39(8):37-42.

PMID:921561
Abstract

Histochemical investigation of 32 biopsy specimens of the muscular tissue taken in patients with Erb's myopathy and 15 bioptic materials from patients with Charcot--Marie--Tooth's amyotrophy was carried out. Characteristics of distribution of enzymes (succinate dehydrogenase, lactate dehydrogenase) in the muscular tissue of the patients referred to above are presented. A quantitative evaluation of the activity of enzymes was made by the method of count of granules of diphormazan with subsequent treatment of data by the statistical variation method.

摘要

对32例埃尔布肌病患者的肌肉组织活检标本以及15例夏科-马里-图斯型肌萎缩患者的活检材料进行了组织化学研究。给出了上述患者肌肉组织中酶(琥珀酸脱氢酶、乳酸脱氢酶)的分布特征。采用双甲臜颗粒计数法对酶活性进行定量评估,随后用统计变异法处理数据。

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