Sava H P, McDonnell J T
Department of Electrical Engineering, University of Edinburgh, U.K.
IEEE Trans Biomed Eng. 1996 Jul;43(7):734-42. doi: 10.1109/10.503181.
This paper investigates the impact of the lung-thorax and heart-valve system on the overall spectral composition of the externally recorded heart sounds. The study concentrates in the case of the first and the second heart sounds for normal patients and patients before and after implantation of a mechanical valve in the mitral or aortic position. The analysis is performed using a modified forward-backward overdetermined Prony's method (MFBPM) which uses a forward-backward mean filter and a modified procedure for estimating the position of the signal poles. In terms of the normalized cross-correlation coefficient, this method has an average modeling accuracy of 99.62% for representing the first and second heart sounds and an average least square time-domain error of 0.43%. Results obtained from 40 subjects show that the condition of the native mitral or aortic valve affects mostly the distribution of the amplitudes of the spectral components, whereas the number of the spectral components or their respective relative energy remains more or less unchanged. It has been found that the amplitudes of frequency components in the range 120-250 Hz are more affected by abnormalities of native mitral valves. Furthermore, in the case of the second heart sound the region 250-400 Hz has been found to be more affected by abnormalities in the aortic valve. It has also been found that the mechanical prosthetic heart valve affects mostly the spectrum beyond 400 Hz. A clear difference has been observed in the frequency spectrum above 400 Hz between both normally and abnormally functioning native valves and normally functioning mechanical valves. Preliminary results in some malfunctioning cases of mechanical prosthesis suggest that spectral components beyond 400 Hz can be used to monitor the condition of these prostheses.
本文研究了肺-胸和心脏瓣膜系统对外记录心音整体频谱成分的影响。该研究主要关注正常患者以及二尖瓣或主动脉瓣位置植入机械瓣膜前后患者的第一心音和第二心音情况。分析采用了一种改进的前向-后向超定 Prony 方法(MFBPM),该方法使用前向-后向均值滤波器以及一种用于估计信号极点位置的改进程序。就归一化互相关系数而言,该方法在表示第一心音和第二心音时的平均建模精度为 99.62%,平均最小二乘时域误差为 0.43%。从 40 名受试者获得的结果表明,天然二尖瓣或主动脉瓣的状况主要影响频谱成分的幅度分布,而频谱成分的数量或其各自的相对能量或多或少保持不变。已发现 120 - 250 Hz 范围内频率成分的幅度受天然二尖瓣异常的影响更大。此外,在第二心音的情况下,已发现 250 - 400 Hz 区域受主动脉瓣异常的影响更大。还发现机械人工心脏瓣膜主要影响 400 Hz 以上的频谱。在 400 Hz 以上的频谱中,正常和异常功能的天然瓣膜与正常功能的机械瓣膜之间观察到明显差异。一些机械假体故障案例的初步结果表明,400 Hz 以上的频谱成分可用于监测这些假体的状况。