• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Primary structure and biological activity of hemoglobin-related hypothalamic peptides.

作者信息

Galoyan A A

机构信息

Institute of Biochemistry, NAS RA, Yerevan, Republic of Armenia.

出版信息

Biopolymers. 1997;43(2):135-7. doi: 10.1002/(SICI)1097-0282(1997)43:2<135::AID-BIP6>3.0.CO;2-W.

DOI:10.1002/(SICI)1097-0282(1997)43:2<135::AID-BIP6>3.0.CO;2-W
PMID:9216249
Abstract

Five individual fractions from bovine hypothalamic extract, displaying coronary constrictory activity, were isolated and sequenced. All of them belong to the hemorphin group of hemoglobin-derived peptides. These peptides bind calmodulin and activate calmodulin-dependent enzymes. The relationship of isolated peptides with other members of the hemorphin group is discussed. Several new fragments of hemoglobin alpha- and beta-chains with yet unidentified activity were obtained from the same source. Their amino acid sequences have considerable overlap with the known sequences of hemoglobin fragments isolated from other tissues.

摘要

相似文献

1
Primary structure and biological activity of hemoglobin-related hypothalamic peptides.
Biopolymers. 1997;43(2):135-7. doi: 10.1002/(SICI)1097-0282(1997)43:2<135::AID-BIP6>3.0.CO;2-W.
2
Isolation of endogenous hemorphin-related hemoglobin fragments from bovine brain.
Biochem Biophys Res Commun. 1994 Jul 15;202(1):410-5. doi: 10.1006/bbrc.1994.1943.
3
Structure of hypothalamic coronaro-constrictory peptide factors.下丘脑冠状动脉收缩肽因子的结构
Neurochem Res. 1992 Dec;17(12):1217-21. doi: 10.1007/BF00968403.
4
Isolation and characterization of four antibacterial peptides from bovine hemoglobin.从牛血红蛋白中分离和鉴定四种抗菌肽。
Peptides. 2006 Sep;27(9):2082-9. doi: 10.1016/j.peptides.2006.03.033. Epub 2006 May 30.
5
Bovine hemoglobin: an attractive source of antibacterial peptides.牛血红蛋白：抗菌肽的一个有吸引力的来源。
Peptides. 2008 Jun;29(6):969-77. doi: 10.1016/j.peptides.2008.01.011. Epub 2008 Jan 31.
6
The hemorphins: a new class of opioid peptides derived from the blood protein hemoglobin.血啡肽：一类源自血液蛋白血红蛋白的新型阿片肽。
Biopolymers. 1997;43(2):147-56. doi: 10.1002/(SICI)1097-0282(1997)43:2<147::AID-BIP8>3.0.CO;2-V.
7
Hemoglobin as a source of endogenous bioactive peptides: the concept of tissue-specific peptide pool.血红蛋白作为内源性生物活性肽的来源：组织特异性肽库的概念。
Biopolymers. 1997;43(2):171-88. doi: 10.1002/(SICI)1097-0282(1997)43:2<171::AID-BIP10>3.0.CO;2-O.
8
Opioid peptides derived from hemoglobin: hemorphins.源自血红蛋白的阿片样肽：血啡肽。
Biopolymers. 1997;43(2):75-98. doi: 10.1002/(SICI)1097-0282(1997)43:2<75::AID-BIP2>3.0.CO;2-X.
9
Cathepsin D is a good candidate for the specific release of a stable hemorphin from hemoglobin in vivo: VV-hemorphin-7.组织蛋白酶D是体内从血红蛋白中特异性释放稳定的血啡肽（VV-血啡肽-7）的良好候选物。
Biochem Biophys Res Commun. 1998 May 29;246(3):719-24. doi: 10.1006/bbrc.1998.8614.
10
Isolation and characterization of two opioid peptides from a bovine hemoglobin peptic hydrolysate.从牛血红蛋白胃蛋白酶水解物中分离和鉴定两种阿片肽。
Biochem Biophys Res Commun. 1992 Nov 30;189(1):101-10. doi: 10.1016/0006-291x(92)91531-t.

引用本文的文献

1
The Role of LVV-H7 in Alcohol-Induced Reward Mechanisms.LVV-H7在酒精诱导的奖赏机制中的作用。
Addict Biol. 2025 Sep;30(9):e70086. doi: 10.1111/adb.70086.
2
Receptorphin: a conserved peptide derived from the sequence of the opioid receptor, with opioid displacement activity and potent antiproliferative actions in tumor cells.受体啡肽：一种源自阿片受体序列的保守肽，具有阿片类置换活性和对肿瘤细胞的强效抗增殖作用。
BMC Pharmacol. 2001;1:9. doi: 10.1186/1471-2210-1-9. Epub 2001 Nov 27.
3
Fragments of functional proteins: role in endocrine regulation.
功能性蛋白质片段：在内分泌调节中的作用
Neurochem Res. 1999 Sep;24(9):1117-24. doi: 10.1023/a:1020756202644.