Watanabe T, Yasuda Y, Tanaka H, Akiguchi I
Department of Neurology, Otsu Red Cross Hospital.
Rinsho Shinkeigaku. 1997 Mar;37(3):243-8.
A 60-year-old man developed disorientation, euphoria, hyperactive behavior, mental confusion, and a moderate decrease of cognition during the course of relapsing polychondritis with bilateral auricular chondritis, sensorineural hearing loss, episcleritis and nasal chondritis. An electroencephalogram showed diffuse slow wave abnormality. The CSF analysis revealed pleocytosis and increased protein. MRI with contrast showed enhancement and edema in bilateral medial temporal regions. These abnormal findings improved markedly with the treatment of corticosteroids. This is the first Japanese case report of relapsing polychondritis presenting as mental disorders.
一名60岁男性在复发性多软骨炎病程中出现定向障碍、欣快感、多动行为、精神错乱以及认知能力中度下降，该患者伴有双侧耳廓软骨炎、感音神经性听力损失、巩膜外层炎和鼻软骨炎。脑电图显示弥漫性慢波异常。脑脊液分析显示细胞数增多和蛋白升高。增强磁共振成像显示双侧内侧颞叶区域强化和水肿。经皮质类固醇治疗后，这些异常表现明显改善。这是日本首例关于以精神障碍为表现的复发性多软骨炎的病例报告。
