Chiron C, Jambaque I, Nabbout R, Lounes R, Syrota A, Dulac O
Hospital F. Joliot, Department of Medical Research, Orsay, France.
Brain. 1997 Jun;120 ( Pt 6):1057-65. doi: 10.1093/brain/120.6.1057.
The development of functional brain asymmetry during childhood is confirmed by changes in cerebral blood flow measured at rest using dynamic single photon emission computed tomography. Between 1 and 3 years of age, the blood flow shows a right hemispheric predominance, mainly due to the activity in the posterior associative area. Asymmetry shifts to the left after 3 years. The subsequent time course of changes appear to follow the emergence of functions localized initially on the right, but later on the left hemisphere (i.e. visuospatial and later language abilities). These findings support the hypothesis that, in man, the right hemisphere develops its functions earlier than the left.
通过使用动态单光子发射计算机断层扫描在静息状态下测量脑血流量的变化,证实了儿童期功能性脑不对称的发展。在1至3岁之间,血流显示右半球占优势,这主要是由于后联合区的活动。3岁后不对称性转移到左侧。随后的变化时间进程似乎遵循最初定位于右侧但后来定位于左侧半球的功能的出现(即视觉空间能力和后来的语言能力)。这些发现支持了这样一种假设,即在人类中,右半球比左半球更早地发展其功能。