Wideman C H, Murphy H M, Tumwesigye S
Department of Biology, John Carroll University, Cleveland, Ohio 44118, USA.
Appetite. 1997 Jun;28(3):189-200. doi: 10.1006/appe.1996.0076.
Vasopressin-deficient (DI) and vasopressin-containing (LE) rats were given continuous access to 32% sucrose and 32% polycose solutions under ad-libitum and food-restricted conditions in a long-term preference test. Although all animals preferred Polycose to sucrose in both conditions, food restriction introduced a stress that significantly increased the consumption of Polycose in DI rats. Considering total caloric intake, Polycose was preferred by both strains only under food restriction and the effect was greatly exacerbated in DI animals compared to LE animals. The differences observed between DI and LE animals in response to ad-libitum feeding and food-restriction stress indicate that vasopressin, directly and/or indirectly, influences the physical and metabolic functions and processes of the animals, which, in turn, affect their intake of Polycose.
在一项长期偏好测试中，给缺乏血管加压素（尿崩症，DI）和含有血管加压素（LE）的大鼠在自由进食和食物限制条件下持续提供32%的蔗糖溶液和32%的多糖溶液。尽管在两种条件下所有动物都更喜欢多糖而非蔗糖，但食物限制引入了一种应激，显著增加了DI大鼠对多糖的消耗量。考虑到总热量摄入，只有在食物限制条件下两种品系的大鼠都更喜欢多糖，并且与LE动物相比，DI动物的这种效应大大加剧。DI和LE动物在自由进食和食物限制应激反应方面观察到的差异表明，血管加压素直接和/或间接地影响动物的生理和代谢功能及过程，进而影响它们对多糖的摄入量。
