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大鼠常量营养素选择的几何分析

Geometric analysis of macronutrient selection in the rat.

作者信息

Simpson S J, Raubenheimer D

机构信息

Department of Zoology, University of Oxford, UK.

出版信息

Appetite. 1997 Jun;28(3):201-13. doi: 10.1006/appe.1996.0077.

DOI:10.1006/appe.1996.0077
PMID:9218094
Abstract

A conceptual framework is introduced which has been derived from work on insects. The scheme is intended to integrate studies of diet selection, regulation of amounts eaten, nutrient utilization, body composition and animal performance. Aspects of framework are illustrated with published data on macronutrient selection in the rat. An animal is viewed as moving through a multidimensional nutrient space, which is bounded by axes representing each required nutrient and within which lie optimal points of intake and nutrient allocation ("targets"). The aim is first to estimate the location of these functional optima experimentally, and then to interpret the responses of animals which are constrained from reaching them ("decisions of best compromise"). The framework can then be used to interpret data from animals reared under differing environmental conditions and to compare animals of differing developmental stage, genotype or nutritional state.

摘要

本文引入了一个源自昆虫研究的概念框架。该方案旨在整合饮食选择、食量调节、营养物质利用、身体组成和动物性能等方面的研究。文中用已发表的关于大鼠常量营养素选择的数据对框架的各个方面进行了说明。动物被视为在一个多维营养空间中移动,该空间由代表每种必需营养素的轴界定,其中存在摄入和营养分配的最佳点(“目标”)。目的首先是通过实验估计这些功能最优值的位置,然后解释动物在无法达到这些最优值时的反应(“最佳折衷决策”)。然后,该框架可用于解释在不同环境条件下饲养的动物的数据,并比较不同发育阶段、基因型或营养状态的动物。

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