Soslow R A, Yin P, Steinberg C R, Yang G C
Department of Pathology, New York Hospital-Cornell Medical Center, New York 10021, USA.
Diagn Cytopathol. 1997 Jul;17(1):50-3. doi: 10.1002/(sici)1097-0339(199707)17:1<50::aid-dc10>3.0.co;2-9.
We present the cytological features of hepatic epithelioid hemangioendothelioma (EH), which is considered to be a vascular proliferation of intermediate malignant potential. The case report concerns a 52-yr-old previously healthy man discovered to have multiple hepatic masses upon evaluation for abnormal liver function tests. Fine-needle aspiration demonstrated a neoplasm composed of interanastomosing epithelioid cells that contained intracytoplasmic lumens. Histologic sections, immunohistochemistry, and ultrastructural evaluation were confirmatory. Although hepatic EH is a rare tumor, its characteristic cytological, histological, and ultrastructural features permit a straightforward diagnosis. It is important to distinguish this entity from adenocarcinoma and angiosarcoma because long-term disease-free survival is possible, especially in the setting of orthotopic liver transplantation.
我们展示了肝上皮样血管内皮瘤（EH）的细胞学特征，该肿瘤被认为是一种具有中等恶性潜能的血管增殖性病变。该病例报告涉及一名52岁既往健康的男性，在评估肝功能异常时发现有多个肝脏肿块。细针穿刺显示肿瘤由相互吻合的上皮样细胞组成，这些细胞含有胞质内管腔。组织学切片、免疫组化和超微结构评估均证实了诊断。尽管肝EH是一种罕见肿瘤，但其特征性的细胞学、组织学和超微结构特征有助于直接诊断。将该病变与腺癌和血管肉瘤区分开来很重要，因为有可能实现长期无病生存，尤其是在原位肝移植的情况下。
