Akhtar W, Edwards H G, Farwell D W, Nutbrown M
University of Bradford, UK.
Spectrochim Acta A Mol Biomol Spectrosc. 1997 Jul 15;53A(7):1021-31. doi: 10.1016/s1386-1425(97)00055-3.
Fourier-transform Raman microscopic spectra of normal, untreated and bleached hair fibres are presented. Vibrational assignments are made and differences are ascribed to the production of cysteic acid from cysteine. Changes in conformation associated with the disulphide bond in the keratotic component are noted from the v(CSSC) vibrational modes at wave numbers near 500 cm-1. Raman spectra of hair root ends have also been investigated with a diminution in cysteine content being observed. Application of the technique to the biomedical investigation of healthy and diseased hair is proposed.
本文展示了正常、未处理和漂白毛发纤维的傅里叶变换拉曼显微光谱。进行了振动归属，并将差异归因于半胱氨酸生成磺基丙氨酸。从波数接近500 cm-1处的v(CSSC)振动模式可以看出，角质化成分中与二硫键相关的构象变化。还研究了发根末端的拉曼光谱，观察到半胱氨酸含量减少。建议将该技术应用于健康和患病毛发的生物医学研究。
