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¹¹¹铟-二乙三胺五乙酸-奥曲肽闪烁扫描术在诊断肺神经内分泌肿瘤和非神经内分泌肿瘤中的应用。初步结果。

Use of 111In-DTPA-octreotide scintigraphy in the diagnosis of neuroendocrine and non-neuroendocrine tumors of the lung. Preliminary results.

作者信息

Oliaro A, Filosso P L, Bello M, Casadio C, Angusti T, Masaneo I, Maggi G, Bisi G

机构信息

Department of Thoracic Surgery, University of Turin, Italy.

出版信息

J Cardiovasc Surg (Torino). 1997 Jun;38(3):313-5.

PMID:9219485
Abstract

BACKGROUND

The authors report their preliminary experience and results of the use of 111In-DTPA-octreotide scintigraphy (octreoscan) in the staging of neuroendocrine and non-neuroendocrine tumors of the lung.

MATERIALS AND METHODS

From July 1995 to May 1996 twenty-six scintigraphic studies were performed in patients affected by lung cancer at the Department of Thoracic Surgery and at the Service of Nuclear Medicine of the University of Turin.

RESULTS

Scintigraphy made it possible to detect the lesion in all the patients affected by neuroendocrine tumors and in 63.2% of the patients affected by non-neuroendocrine neoplasm of the lung. Scintigraphy also revealed mediastinal lymphnodal metastases in patients in which thoracic CT scan was negative: this result was confirmed by postoperative TNM.

CONCLUSIONS

The authors stress the importance of 111In-DTPA-octreotide scintigraphy in a correct procedure of staging of neuroendocrine and non-neuroendocrine tumors of the lung and in the follow-up of neoplastic patients.

摘要

背景

作者报告了他们使用铟 - 111 - 二乙三胺五醋酸奥曲肽闪烁扫描术(奥曲肽扫描)对肺部神经内分泌和非神经内分泌肿瘤进行分期的初步经验和结果。

材料与方法

1995年7月至1996年5月期间,都灵大学胸外科和核医学科对26例肺癌患者进行了闪烁扫描研究。

结果

闪烁扫描术能够检测出所有受神经内分泌肿瘤影响的患者以及63.2%受肺部非神经内分泌肿瘤影响的患者中的病变。闪烁扫描术还揭示了胸部CT扫描呈阴性的患者的纵隔淋巴结转移情况:这一结果得到了术后TNM分期的证实。

结论

作者强调铟 - 111 - 二乙三胺五醋酸奥曲肽闪烁扫描术在正确进行肺部神经内分泌和非神经内分泌肿瘤分期以及肿瘤患者随访过程中的重要性。

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