Samuelsson H, Jensen C, Ekholm S, Naver H, Blomstrand C
Dept. of Psychology, University of Göteborg, Sweden.
Cortex. 1997 Jun;33(2):271-85. doi: 10.1016/s0010-9452(08)70004-2.
Anatomical and neurological correlates of visuospatial neglect were studied in 53 patients with a CT-documented right hemisphere stroke. Evidence of neglect at the acute stage poststroke was strongly related to large lesions involving the middle temporal gyrus and/or the temporo-parietal paraventricular white matter. Thus, out of 18 patients with evidence of visuospatial neglect at the acute stage, 12 showed a lesion in the middle temporal gyrus and/or the deep temporo-parietal white matter. Among the 35 patients that failed to show visuospatial neglect, only one patient had a lesion within these areas. Comparing those patients who recovered from neglect with those that did not, a high correlation was found between persisting neglect and a lesion involving the paraventricular white matter in the temporal lobe. On the basis of above findings, it was suggested that a simultaneous damage to the cortico-thalamic system for regulation of arousal and to the neural systems mediating visual orienting, is likely to be followed by persisting neglect symptoms.
对53例经CT证实为右半球中风的患者进行了视觉空间忽视的解剖学和神经学相关性研究。中风急性期忽视的证据与涉及颞中回和/或颞顶脑室旁白质的大面积病变密切相关。因此，在18例急性期有视觉空间忽视证据的患者中，12例显示颞中回和/或颞顶深部白质有病变。在35例未表现出视觉空间忽视的患者中，只有1例在这些区域有病变。将从忽视中恢复的患者与未恢复的患者进行比较，发现持续忽视与颞叶脑室旁白质病变之间存在高度相关性。基于上述发现，有人提出，调节觉醒的皮质-丘脑系统和介导视觉定向的神经系统同时受损，可能会导致持续的忽视症状。
