Brown M
University of Rochester Clinical Group, NY 14618-2618, USA.
Semin Cutan Med Surg. 1997 Jun;16(2):113-21. doi: 10.1016/s1085-5629(97)80005-3.
Prognosis and survival for patients diagnosed with melanoma depends on a number of interrelated factors, including histological, clinical, immunologic, and surgical parameters. Tumor thickness and depth of invasion is the most important prognostic factor, and helps to guide treatment and management plans. Besides tumor thickness, other histological criteria include melanoma growth phase (nodal v. vertical), host response, angiolymphatic invasion, mitotic rate, regression, satellitosis, and neurotropism. Important clinical prognostic factors include anatomic location of the melanoma and the patient's age and sex. Surgical factors to be examined involve excisional margin size, and elective lymph node dissection. Finally, the staging of patients with melanomas (nodal or visceral metastases) helps to define survival.
被诊断为黑色素瘤的患者的预后和生存情况取决于许多相互关联的因素，包括组织学、临床、免疫和手术参数。肿瘤厚度和浸润深度是最重要的预后因素，并有助于指导治疗和管理计划。除肿瘤厚度外，其他组织学标准包括黑色素瘤生长阶段（结节性与垂直性）、宿主反应、血管淋巴管浸润、有丝分裂率、消退、卫星灶形成和嗜神经性。重要的临床预后因素包括黑色素瘤的解剖位置以及患者的年龄和性别。需要检查的手术因素包括切除边缘大小和选择性淋巴结清扫。最后，黑色素瘤患者的分期（淋巴结或内脏转移）有助于确定生存情况。
