Vincent D
Service de Médecine Interne, Hôpital Louis Mourier, Colombes.
Allerg Immunol (Paris). 1997 Mar;29(3):63, 66-8.
A relationship between asthma and gastro-oesophegal reflux (RGO) has been suspected for a long time but never proved. Many studies have shown improvement of asthma by treatment of RGO. The predictive factors of this improvement are unknown. After a short description of the epidemiology of RGO, in general and asthmatic populations, the mechanisms that link the two pathologies have been evaluated, the first consideration being the relationship between bronchial reactivity and RGO, to suggest a practical procedure for asthmatics, with regard to RGO. For therapy, inhibitors of the proton pump arise naturally.
长期以来，人们一直怀疑哮喘与胃食管反流（RGO）之间存在关联，但从未得到证实。许多研究表明，通过治疗RGO可改善哮喘症状。然而，这种改善的预测因素尚不清楚。在简要描述了一般人群和哮喘患者中RGO的流行病学情况后，我们评估了将这两种病症联系起来的机制，首先考虑的是支气管反应性与RGO之间的关系，从而为哮喘患者提出了针对RGO的实用治疗方案。在治疗方面，质子泵抑制剂是自然而然的选择。
