Sewell W A, Brennan V M, Donaghy M, Chapel H M
Department of Immunology, John Radcliffe Hospital, Oxford, UK.
J Neurol Neurosurg Psychiatry. 1997 Jul;63(1):106-9. doi: 10.1136/jnnp.63.1.106.
High dose intravenous immunoglobulin therapy is becoming the established maintenance treatment for several neurological conditions. Therapeutic immunoglobulin is expensive and its administration is time consuming. Efficacy is variable and must be closely monitored. Here, we show that self infused immunoglobulin at home, combined with daily functional strength diaries to predict dose and dosage intervals, is effective, time saving, and convenient for both patients and medical staff.
大剂量静脉注射免疫球蛋白疗法正成为多种神经系统疾病的既定维持治疗方法。治疗性免疫球蛋白价格昂贵,其给药过程耗时。疗效存在差异,必须密切监测。在此,我们表明患者在家自行注射免疫球蛋白,结合每日功能强度记录以预测剂量和给药间隔,对患者和医护人员而言都是有效、省时且方便的。