Abath F G, Werkhauser R C
Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhaes Fundacao Oswaldo Cruz, Cidade Universitaria, Recife-PE, Brasil.
Parasite Immunol. 1996 Jan;18(1):15-20. doi: 10.1046/j.1365-3024.1996.d01-6.x.
Some structural, biophysical and molecular features of the tegument are shown, highlighting their changes during maturation as important adaptative mechanisms for the survival of the parasite and resistance to immune attack. On the other hand, many antigens, targets of the immune response against the schistosome, are located on the tegument. Some of the features of these molecules are presented and the possibilities of using them in the immunological control of the disease are discussed.
展示了皮层的一些结构、生物物理和分子特征,突出了它们在成熟过程中的变化,这些变化是寄生虫生存和抵抗免疫攻击的重要适应性机制。另一方面,许多作为针对血吸虫免疫反应靶点的抗原位于皮层上。介绍了这些分子的一些特征,并讨论了将它们用于该疾病免疫控制的可能性。