Toker R, Flusser D, Hertzanu Y, Sukenik S
Medical Dept., Soroka Medical Center, Beer Sheba.
Harefuah. 1997 Jun 1;132(11):759-61, 823.
A 51-year-old immigrant from the Caucasus had had chronic tophaceous gout for over 20 years, but had never been treated with anti-hyperuricemic drugs. He had developed large, multiple tophi in many locations, including both ankles and feet. The enormous size and unique location of the tophi caused considerable pain, and difficulty in standing and on walking. Since surgical removal of the tophi was refused by the patient, a course of allopurinol, 300 mg/day, was begun.
一名来自高加索地区的51岁移民患慢性痛风石性痛风已有20多年,但从未接受过抗高尿酸血症药物治疗。他在包括双踝和双脚在内的许多部位出现了大量的痛风石。痛风石巨大的尺寸和独特的位置造成了相当大的疼痛,以及站立和行走困难。由于患者拒绝手术切除痛风石,于是开始使用别嘌醇进行治疗,剂量为每日300毫克。