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一名有别嘌醇中毒病史患者的慢性痛风石性痛风。

Chronic tophaceous gout in a patient with a history of allopurinol toxicity.

作者信息

Naas J E, Sanders L J

机构信息

VA Medical Center, Lebanon, Pennsylvania, USA.

出版信息

Cutis. 1998 Nov;62(5):239-41.

PMID:9836057
Abstract

We present an unusual complication of chronic tophaceous gout in a 63-year-old man with a 27-year history of gout, who could not be treated with allopurinol due to previous allopurinol-induced neutropenia. The patient presented with a progressively enlarging, painful mass on the bottom of his right foot, which caused difficulty wearing shoes and walking. Extirpation of the tophus and first metatarsophalangeal joint arthroplasty were successfully employed for management of this condition.

摘要

我们报告了一名63岁男性慢性痛风石性痛风的罕见并发症,该患者有27年痛风病史,因既往使用别嘌醇导致中性粒细胞减少而无法使用别嘌醇治疗。患者右足底出现一个逐渐增大的疼痛性肿块,导致穿鞋和行走困难。成功采用痛风石切除术和第一跖趾关节置换术来治疗这种情况。

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