Ceelen W, Kerremans I, Lutz-Dettinger N, Vandenbroeck P, de Hemptinne B
Department of Pediatric Surgery, University Hospital, Gent University Medical School, Belgium.
Acta Chir Belg. 1997 Jun;97(3):148-50.
Wilms' tumour (nephroblastoma) is one of the most common solid malignant tumours in infancy and childhood. In about 40% of cases, invasion of the renal vein is present. Rarely, these tumours extend into the inferior vena cava and right atrium. We discuss a 7-week-old girl who presented with acute massive pulmonary embolism, and was found to have a large tumour of the left kidney. Later on, the diagnosis of Wilms' tumour was confirmed. Wilms' tumour presenting as massive pulmonary embolism is extremely rare; to our knowledge this is the fourth case described in literature. We review the cases previously described, and comment on the diagnostic and therapeutic features of this clinical entity.
肾母细胞瘤是婴幼儿期最常见的实体恶性肿瘤之一。约40%的病例存在肾静脉侵犯。这些肿瘤很少延伸至下腔静脉和右心房。我们讨论一名7周大的女童,她因急性大面积肺栓塞就诊,检查发现左肾有一个大肿瘤。后来,肾母细胞瘤的诊断得到证实。以大面积肺栓塞为表现的肾母细胞瘤极为罕见;据我们所知,这是文献中描述的第四例。我们回顾了先前描述的病例,并对该临床实体的诊断和治疗特点进行了评论。