Fernández-Suárez A, Carbajo S, López J M, Carbajo-Pérez E
Department of Morphology and Cell Biology, Faculty of Medicine, University of Oviedo, Spain.
Histol Histopathol. 1997 Jul;12(3):729-34.
The expression of argyrophilic nucleolar organizer regions (AgNORs) was studied in the different secretory cell types of the Harderian gland of male and female Syrian hamsters during postnatal development. Mean AgNOR area was calculated for each cell type in paraffin sections from 7-, 14-, 21-, 28-, 45- and 90-day-old animals. AgNOR content was similar in male type I-cells and in female cells, decreasing in both cell types from the 7th to the 14th day, increasing afterwards at the 21st day, and remaining at relatively stable levels from that point to the end of the study. AgNOR content of male type II-cells was greater than in other cell type studied, and was greater in 45- and 90-day-old animals than in 28-day-olds. Changes of AgNOR content in type I-cells of male and female hamsters during the first two weeks seem to be related to changes in proliferative activity while metabolic activity might be responsible for changes taking place later on. Our results also support that male type I- and type II-cells have a different biological behaviour and that type II-cells are far from being degenerating cells.
在出生后发育过程中，对叙利亚仓鼠雄性和雌性哈德氏腺不同分泌细胞类型中的嗜银核仁组织区（AgNORs）表达进行了研究。计算了7日龄、14日龄、21日龄、28日龄、45日龄和90日龄动物石蜡切片中每种细胞类型的平均AgNOR面积。雄性I型细胞和雌性细胞中的AgNOR含量相似，两种细胞类型中的含量均在第7天至第14天下降，之后在第21天增加，并从该时间点至研究结束保持在相对稳定的水平。雄性II型细胞的AgNOR含量高于所研究的其他细胞类型，且在45日龄和90日龄动物中高于28日龄动物。雄性和雌性仓鼠I型细胞中AgNOR含量在前两周的变化似乎与增殖活性的变化有关，而代谢活性可能是随后发生变化的原因。我们的结果还支持雄性I型和II型细胞具有不同的生物学行为，且II型细胞远非退化细胞。
