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梨形四膜虫细胞内钙离子转运系统的细胞内分布及特征

Intracellular distribution and characteristics of Ca(2+)-transporting systems in cells of ciliate protozoan Tetrahymena pyriformis.

作者信息

Yurkov I S, Zinchenko V P, Makarov P R, Kuznetsova S M

机构信息

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region.

出版信息

Membr Cell Biol. 1997;10(5):565-72.

PMID:9225260
Abstract

A significant digitonin-sensitive calcium pool has been shown to exist in Tetrahymena pyriformis cells. In the presence of exogenic energy sources, calcium released from the digitonin-sensitive pool can be accumulated by mitochondria or endoplasmic reticulum. The kinetic characteristics of the mitochondrial and reticulum systems of Ca2+ transport and their sensitivity to various inhibitors were studied.

摘要

已证实在梨形四膜虫细胞中存在一个对洋地黄皂苷敏感的重要钙池。在外源性能源存在的情况下,从洋地黄皂苷敏感池中释放的钙可被线粒体或内质网积累。研究了线粒体和内质网钙转运系统的动力学特性及其对各种抑制剂的敏感性。

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