Rezakhani A, Edjtehadi M, Szabuniewicz M
Can J Comp Med. 1977 Oct;41(4):389-95.
The effects of epinephrine (5 microgram/kg of body weight) on ten unanesthetized sheep were experimentally tested: all sheep displayed serious arrhythmias. Sheep anesthetized with thiopental and thiopental/halothane combination displayed cardiac arrhythmias of the order of 10% and 20% respectively. Challenge injections of epinephrine (5 microgram/kg of body weight) to ten sheep anesthetized with thiopental, and to the same number of animals after 45 minutes of anesthesia with thiopental/halothane, produced serious arrhythmias. However, following preanesthetic treatment with acepromazine maleate (0.5 mg/kg) to 15 sheep, serious arrhythmias were prevented in all of them when they were given arrhythmic doses of epinephrine.
对10只未麻醉的绵羊进行了肾上腺素（5微克/千克体重）作用的实验测试：所有绵羊均出现严重心律失常。用硫喷妥钠和硫喷妥钠/氟烷组合麻醉的绵羊分别有10%和20%出现心律失常。对10只硫喷妥钠麻醉的绵羊以及硫喷妥钠/氟烷麻醉45分钟后的相同数量动物进行肾上腺素（5微克/千克体重）激发注射，均产生严重心律失常。然而，对15只绵羊术前用马来酸乙酰丙嗪（0.5毫克/千克）治疗后，当给予致心律失常剂量的肾上腺素时，所有绵羊均未出现严重心律失常。
