Kligman M, Bernfeld B, Roffman M
Dept. of Orthopedic Surgery, Carmel Medical Center, Haifa.
Harefuah. 1997 May 1;132(9):627-9, 679.
We present a 9-year-old girl who had chronic recurrent multifocal osteomyelitis. The bones involved were: right clavicle, distal fibula (bilateral), left sacroiliac and right wrist. After 10 years of follow-up; she is asymptomatic but presents radiological evidence of lesions in the right clavicle and left sacroiliac joint. The diagnosis was made by exclusion criteria. The biopsy and results of cultures from various bones were negative 4 times. Although chronic recurrent multifocal osteomyelitis is rare, it should be considered in the differential diagnosis of acute or chronic osteomyelitis and neoplasma. Its recognition avoids unnecessary laboratory tests and antibiotic therapy.
我们报告一名患有慢性复发性多灶性骨髓炎的9岁女孩。受累骨骼包括:右锁骨、双侧腓骨远端、左骶髂关节和右手腕。经过10年的随访;她没有症状,但右锁骨和左骶髂关节有病变的影像学证据。诊断是根据排除标准做出的。来自不同骨骼的活检和培养结果4次均为阴性。虽然慢性复发性多灶性骨髓炎很少见,但在急性或慢性骨髓炎及肿瘤的鉴别诊断中应予以考虑。认识到这一点可避免不必要的实验室检查和抗生素治疗。