Wåler S M
Dental Faculty, University of Oslo, Norway.
Acta Odontol Scand. 1997 Jun;55(3):198-200. doi: 10.3109/00016359709115416.
Volatile sulfur-containing compounds (VSC) are known to constitute the major component of halitosis. Aqueous solutions of zinc salts have been shown to reduce the levels of VSC produced orally. The aim of the present study was to examine whether zinc could be made available in the oral cavity and inhibit VSC production when delivered by a chewing gum. VSC measurements were carried out on the 'morning breath' of 11 test subjects and re-examined after the use of test solutions containing 0.02% zinc chloride, 0.2% chlorhexidine, or water or the use of chewing gums containing 2 mg, 0.5 mg, or 0 mg zinc acetate. The results showed that similar amounts of zinc in mouthrinses or chewing gum had the same effect, with a reduction of the oral VSC of 45%. Chewing gum thus seems to be a viable alternative for delivering zinc to reduce VSC levels in the oral cavity.
挥发性含硫化合物（VSC）是口臭的主要成分。锌盐的水溶液已被证明可以降低口腔产生的VSC水平。本研究的目的是检验当通过口香糖递送时，锌是否能在口腔中发挥作用并抑制VSC的产生。对11名受试对象的“晨起口气”进行VSC测量，并在使用含0.02%氯化锌、0.2%氯己定的测试溶液、水或含2mg、0.5mg或0mg醋酸锌的口香糖后重新进行检测。结果表明，漱口水或口香糖中相同量的锌具有相同的效果，可使口腔VSC减少45%。因此，口香糖似乎是递送锌以降低口腔中VSC水平的一种可行替代方法。
