Effects of 6-azauridine on nucleotides, orotic acid, and orotidine in L5178Y mouse lymphoma cells in vitro.
作者信息
Janeway C M, Cha S
出版信息
Cancer Res. 1977 Dec;37(12):4382-8.
PMID:922730
Abstract
摘要
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Inhibition of orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase of human erythrocytes by purine and pyrimidine nucleotides.嘌呤和嘧啶核苷酸对人红细胞乳清酸磷酸核糖基转移酶和乳清苷-5'-磷酸脱羧酶的抑制作用。
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Polymer-linked 6-azauridine 5'-monophosphate, a resin of high bioaffinity to orotidine-5'-phosphate decarboxylase.聚合物连接的6-氮杂尿苷5'-单磷酸，一种对乳清苷-5'-磷酸脱羧酶具有高生物亲和力的树脂。
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Hereditary Orotic Aciduria and the Excretion of Orotidine.遗传性乳清酸尿症与乳清苷的排泄
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Theoretical drug design: 6-azauridine-5'-phosphate--its X-ray crystal structure, potential energy maps, and mechanism of inhibition of orotidine-5'-phosphate decarboxylase.理论药物设计：6-氮杂尿苷-5'-磷酸——其X射线晶体结构、势能图及对乳清苷-5'-磷酸脱羧酶的抑制机制
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Synthesis of carbocyclic orotidine analogs as potential orotidine decarboxylase inhibitors.作为潜在的乳清苷脱羧酶抑制剂的碳环乳清苷类似物的合成。
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Orotic aciduria and uridine monophosphate synthase: a reappraisal.鸟氨酸氨甲酰转移酶缺乏症和尿苷一磷酸合酶：再评价。
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In brief: Uridine triacetate (Xuriden) for hereditary orotic aciduria.简而言之：用于遗传性乳清酸尿症的三醋酸尿苷（Xuriden）。
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