单发和多发腔隙性脑梗死中的脑血流量
Cerebral blood flow in single and multiple lacunar infarctions.
作者信息
Mochizuki Y, Oishi M, Takasu T
机构信息
Department of Neurology, Nihon University School of Medicine, Tokyo, Japan.
出版信息
Stroke. 1997 Jul;28(7):1458-60. doi: 10.1161/01.str.28.7.1458.
BACKGROUND AND PURPOSE
Single and multiple lacunar infarctions may have some difference in underlying diseases and cerebral blood flows. To determine the difference, we investigated underlying diseases and cerebral blood flows in single and multiple lacunar infarctions.
METHODS
Fifteen cases of lacunar infarction, 10 cases of multiple lacunar infarctions, and 16 control subjects were studied. Regional cerebral blood flow was measured within 14 days after stroke onset with the stable xenon CT method.
RESULTS
The rate of association of diabetes mellitus was higher in the multiple lacunar infarctions group than in the single lacunar infarction group. The blood flow in the cerebral cortex was significantly lower in the multiple lacunar infarctions group than in the single lacunar infarction group. The blood flow change by acetazolamide in the cerebral cortex was significantly lower in the multiple lacunar infarctions group than in the single lacunar infarction group.
CONCLUSIONS
There is some difference in underlying diseases and cerebral blood flows between single and multiple lacunar infarctions.
背景与目的
单发和多发腔隙性脑梗死在基础疾病和脑血流方面可能存在一些差异。为确定这些差异，我们对单发和多发腔隙性脑梗死的基础疾病和脑血流进行了研究。
方法
对15例腔隙性脑梗死患者、10例多发腔隙性脑梗死患者和16名对照者进行了研究。在卒中发作后14天内，采用稳定氙CT法测量局部脑血流量。
结果
多发腔隙性脑梗死组糖尿病的关联率高于单发腔隙性脑梗死组。多发腔隙性脑梗死组大脑皮质的血流量显著低于单发腔隙性脑梗死组。多发腔隙性脑梗死组大脑皮质中乙酰唑胺引起的血流变化显著低于单发腔隙性脑梗死组。
结论
单发和多发腔隙性脑梗死在基础疾病和脑血流方面存在一些差异。
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