Hughes R L, Yonas H, Gur D, Latchaw R
Department of Neurology, University of Pittsburgh, Pennsylvania.
Stroke. 1989 Jun;20(6):754-60. doi: 10.1161/01.str.20.6.754.
Cerebral blood flow mapping with stable xenon-enhanced computed tomography (Xe/CT) was performed in conjunction with conventional computed tomography (CT) within the first 8 hours after the onset of symptoms in seven patients with cerebral infarction. Six patients had hemispheric infarctions, and one had a progressive brainstem infarction. Three patients with very low (less than 10 ml/100 g/min) blood flow in an anatomic area appropriate for the neurologic deficit had no clinical improvement by the time of discharge from the hospital; follow-up CT scans of these three patients confirmed infarction in the area of very low blood flow. Three patients with moderate blood flow reductions (15-45 ml/100 g/min) in the appropriate anatomic area had significant clinical improvement from their initial deficits and had normal follow-up CT scans. One patient studied 8 hours after stroke had increased blood flow (hyperemia) in the appropriate anatomic area and made no clinical recovery.
对7例脑梗死患者在症状发作后的最初8小时内，采用稳定氙增强计算机断层扫描（Xe/CT）结合传统计算机断层扫描（CT）进行脑血流图谱绘制。6例患者为半球梗死，1例为进行性脑干梗死。3例在与神经功能缺损相应的解剖区域血流极低（低于10 ml/100 g/分钟）的患者，出院时无临床改善；这3例患者的随访CT扫描证实了血流极低区域的梗死。3例在相应解剖区域血流中度减少（15 - 45 ml/100 g/分钟）的患者，相对于初始缺损有显著的临床改善，且随访CT扫描正常。1例在卒中后8小时接受检查的患者，在相应解剖区域血流增加（充血），且无临床恢复。
